Zhan-Zhuang Tian

Ph.D.& M.D. Associate Professor
1. Neuroendocrinological mechanism of integrative medicine on the modulation of female reproductive disorders 
2. Neuroendocrine-immune mechanism of electroacupuncture on normalizing the subnormal function of hypothalamus-pituitary-adrenal axis



1985-1990 bacholar Hebei Medical University 
1993-1996 masster Beijin University of Traditional Chinese Medicine
2000-2003 Ph.D. Fudan University


1.Shiran Wang, Liting Zhu, Jian Yu, Zhanzhuang Tian. Effect of Nourishing“Yin”-removing “Fire” Chinese herbal mixture on hypothalamic  NKB/NK3R expression in female precocious rats. Evidence-Based Complementary and Alternative Medicine 2014, Article ID 217424,  http://dx.doi.org/10.1155/2014/217424
2. Jing Li, Yanyan Sun, Shiran Wang, Jian Yu, Zhanzhuang Tian. Effects of Nourishing “Yin”-Removing “Fire” Chinese Herb Mixture on the Differential Expression of GABAA Receptor α Subunits in Hypothalamus of Precocious Puberty Female Rats. Chinese Medicine, 2013, 4, 87-96
3.Yan Sun, Jian Yu, Boying Chen , Zhanzhuang Tian. Effect of Nourishing ″Yin″- Removing ″Fire″ Chinese herb mixture on the hypothalamic kisspeptin expression in precocious rats. Journal of Ethnopharmacology, 2010,127:274-279
4.Li Sun, Zhanzhuang Tian , Jianping Wang. A direct cross-talk between interferon-c and sonic hedgehog signaling that leads to the proliferation of neuronal precursor cells. Brain, Behavior, and Immunity 24 (2010) 220–228
5. Hua Zhang, Zhanzhuang Tian, Jianping Wang. Behavioral evaluation of  by elevated plus-maze and Porsolttransgenic mice with CNS expression of IFN- swim test . Neurosci Lett. 2010,479: 287-291.
6.Yan Sun, Zhan-Zhuang Tian, Hong Zhao, Stephen TC Wong, Bo-Ying Chen. Characteristic of hypothalamic kisspeptin expression in the pubertal development of precocious female rats. Neurosci Lett. 2007,420:12-17.
7. Zhan-Zhuang Tian, Hong Zhao, Bo-Ying Chen. Evaluation of the true precocious puberty rats induced by neonatal administration of Danazol: Therapeutic effects of nourishing “Yin”- removing “Fire” Chinese herb mixture. Reprod Biol & Endocrin 2005,3:38.
8. Zhan-Zhuang Tian, Hong Zhao, Bo-Ying Chen. Decreased hypothalamic aromatase in female rats of precocious puberty. Neurosci Lett, 2004, 366(1): 92-96.
9. Hong Zhao, Zhan-Zhuang Tian, Jun-Wei Hao, Bo-Ying Chen. Extragonadal aromatization increases with time after ovariectomy in rat. Reprod Biol & Endocrin, 2005, 3:6.
10. Hong Zhao, Zhan-Zhuang Tian, Bo-Ying Chen. Brain aromatization may involve in electroacupuncture enhancing hypofunction of hypothalamus- pituitary - ovary axis in ovariectomized rats. Brain Res, 2005, 1037 (1-2):164-170.
11.Hong Zhao, Zhan-Zhuang Tian, Yi Feng, Bo-Ying Chen. Circulating estradiol and hypothalamic corticotrophin releasing hormone enhances along with time after ovariectomy in rats: effects of electroacupuncture. Neuropeptides 2005, 39(4): 433-438.
12.Hong Zhao, Zhan-Zhuang Tian, Bo-Ying Chen. Increased corticortropin- releasing hormone release in ovariectomized rats’ paraventricular nucleus: effects of electroacupuncture. Neurosci Lett, 2003, 353(1): 37-40.
13.Hong Zhao, Zhan-Zhuang Tian, Bo-Ying Chen. An important role of corticotropin-releasing hormone in electroacupuncture normalizing the subnormal function of hypothalamus- pituitary-ovary axis in ovariectomized rats. Neurosci Lett, 2003, 349(1): 25-28
14.田占庄,赵 宏,陈伯英. 滋阴泻火中药对性早熟模型大鼠促性腺激素释放激素及其受体mRNA表达的影响 中国中西医结合杂志2003,23(9): 700-704.
15.田占庄,赵 宏,陈伯英. 达那唑诱导的雌性性早熟大鼠GnRH及其受体mRNA的表达 中华内分泌代谢杂志 2003,19(3): 229-231.
16.陈姗姗,俞健,田占庄. 曲谱瑞林治疗真性性早熟的中枢机制 中国新药与临床杂志 2009 28(2):134-137。
17.张彦,马淑兰,陈伯英,田占庄. 针刺对急性手术创伤大鼠下丘脑CRF家族肽及其受体表达的影响,针刺研究,2010, 35(3):163-169.
18.朱黎婷,田占庄.电针对急性手术创伤大鼠海马及下丘脑促肾上腺皮质激素释放因子表达的影响[J]. 针刺研究, 2013, 38(5):369-374
19.田占庄,张立凤,朱培纯. 两种慢性痛大鼠脊髓和脊神经节一氧化氮合酶的表达及电针的影响. 承德医学院学报 2001 18(3) 198-201.
20.田占庄,张立凤,朱培纯.两种慢性痛大鼠脊神经节生长抑素mRNA的表达及电针的影响. 承德医学院学报 2001 18(4)267-271.
 21.Zhan Zhuang Tian, Zhao Hong: Acupuncture Therapy for Menopausal and Perimenopausal Syndrome (Editors: Ying Xia, Xiaoding Cao, Gencheng Wu, Jieshi Cheng, Acupuncture therapy for neurological diseases: A neurobiological view). TSINGHUA and Springer; 1st Edition 2010


Post Box 291, 138 Yi-Xue-Yuan Road
Department of Integrative Medicine and Neurobiology
Shanghai Medical College Fudan University
Shanghai, 200032
People's Republic of China
E-mail: tianvv@shmu.edu.cn 

Department of Integrative Medicine and Neurobiology, School of Basic Medical Sciences of Fudan University copyright © 2014

Address: 138 Yi Xue Yuan Road, Shanghai China