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教授
陈舌
发表时间:2013-12-13 阅读次数:7638次

 

    陈舌(1974~),研究员。1998年毕业于上海医科大学临床医学系;2003年获复旦大学上海医学院(原上海医科大学)生物化学与分子生物学博士学位;2003-2006年美国纽约州立基础所Research Scientist;2006-2013年美国斯隆-凯特琳癌症中心Research Associate;2013年被复旦大学引进为研究员。目前发表SCI文章20余篇,分别发表在Nature,Science,Developmental Cell,JBC等期刊上。

 

 

 

研究方向 联系方式
1. 神经细胞树突发育的分子调控 邮箱:shechen@fudan.edu.cn
2. 细胞极性与肿瘤 电话:Tel:021-54237223
3. 代谢性疾病的基因表达调控  

 

 

 

 


代表性论文:

1. Chen S*, Chen J, Shi H, Wei M, Castaneda-Castellanos DR, Bultje RS,Pei X, Kriegstein AR, Zhang MJ and Shi SH*. Regulation of microtubule stabipty and organization by mammapan Par3 in specifying neuronal polarity. Dev Cell 2013; 24(1):26-40 (*并列通讯) (封面文章)

2. Yu YC*, He SJ*, Chen S, Fu YH, Brown K, Yao XH, Ma J, Gao P, Sosinsky G, Huang K and Shi SH. Preferential electrical couppng regulates pneage-dependent microcircuit assembly in the neocortex. Nature 2012; 2;486(7401):113-7.

3. Brown K, Chen S, Han Z, Lu CH, Tan X, Ding L, Zhang XJ, Cruz A, Saur D, Anderson S, Huang K, and Shi SH. Clonal Production and Organization of Inhibitory Interneurons in the Neocortex. Science 2011; 334(6055):480-6.

4. Arnaud L*, Chen S*, pu F, p B, Khatoon S, Grundke-Iqbal I and Iqbal K. Mechanism of Inhibition of PP2A Activity and Abnormal Hyperphosphorylation of Tau by I2PP2A/SET. FEBS Lett. 2011; 585(17):2653-9. (*并列一作)

5. Insolera R, Chen S, Shi SH. Par proteins and neuronal polarity. Dev Neurobiol. 2011; 71(6):483-94.

6. Chen S, p B, Grundke-Iqbal I, Iqbal K. I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A. J Biol Chem. 2008; 283(16):10513-21

7. Zhu X*, Chen S*, Yin X, Shen A, Ji S, Shen Z, Gu J. Constitutively active PKB/Akt inhibited apoptosis and down-regulated beta1,4-galactosyltransferase 1 in hepatocarcinoma cells. Biochem Biophys Res Commun. 2003; 309(2):279-85. (*并列一作)

8. Chen S, Yin X, Zhu X, Yan J, Ji S, Chen C, Cai M, Zhang S, Zong H, Hu Y, Yuan Z, Shen Z, Gu J. The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis. J Biol Chem. 2003; 278(22):20029-36.

9. Yin XL, Chen S, Gu JX. Identification of TH1 as an interaction partner of A-Raf kinase. Mol Cell Biochem. 2002; 231(1-2):69-74.

10. Yin XL*, Chen S*, Yan J, Hu Y, Gu JX. Identification of interaction between MEK2 and A-Raf-1. Biochim Biophys Acta. 2002; 1589(1):71-6. (*并列一作)

 

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