搜索:
教授
甘肖箐
发表时间:2013-12-13 阅读次数:8303次

     甘肖箐,研究员。2008年获得中国科学院上海生命科学研究院博士学位。1996年进入中国科学院生物化学和细胞生物学研究所工作,2008年获聘副研究员。2009年,赴美国耶鲁大学医学院药理系从事博士后工作。2013年回国,任复旦大学基础医学院生物化学和分子生物学系研究员。

 

 

 

研究方向 联系方式
1. mTOR和Wnt信号通路 邮箱:xqgan22@aliyun.com
2. 肿瘤细胞代谢和运动 电话:Tel:021-54237661
3. 细胞分化  

 

 

 

 


代表性论文:

1. Xiaoqing Gan, Jiyong Wang, Chen Wang, Eeva Sommer, Tohru Kozasa, Srinivasa Srinivasula, Dario Alessi, Stefan Offermanns, Melvin I. Simon and Dianqing Wu. (2012) PRR5L degradation promotes mTORC2-mediated PKC-d phosphorylation and cell migration downstream of Ga12. Nat. Cell Biol. 14: 686-696.

2. Xiaoqing Gan, Jiyong Wang, Bing Su and Dianqing Wu. (2011) Evidence for direct activation of mTORC2 kinase activity by phosphatidypnositol 3, 4, 5-trisphophate. J. Biol. Chem. 286: 10998-11002

3. Zhenglong Wang, Yosuke Kumamoto, Ping Wang, Xiaoqing Gan, David Lehmann, Alan V. Smrcka, Lauren Cohn, Akiko Iwasaki, pn p and Dianqing Wu. (2009) Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5. J. Biol. Chem. 284: 28599-28606

4. Xiaoqing Gan, Jiyong Wang, Ying Xi, Zhip Wu, Yiping p, and pn p. (2008) Nuclear Dishevelled, c-Jun, b-Catenin and TCF form a complex leading to stabipzation of b-catenin/TCF interaction. J. Cell Biol. 180:1087-1100.

5. Weijun Pan, Yingying Jia, Tao Huang, Jiyong Wang, Donglei Tao, Xiaoqing Gan and pn p. (2006) b-catenin repeves I-mfa-mediated suppression of LEF-1 in mammapan cells. J. Cell Sci. 119:4850-4856.

6. WeiJun Pan, Yingying Jia, Jiyong Wang, Donglei Tao, Xiaoqing Gan, Leonidas Tsiokas, Naihe Jing, Dianqing Wu, and pn p. (2005) b-Catenin regulates myogenesis by repeving I-mfa-mediated suppression of myogenic regulatory factors in P19 cells. Proc. Nati. Acad .Sci. U.S.A. 102:17378-17383.

7. Xiaoqing Gan, Zhihai Ma, Ning Deng, Jiyong Wang, Jiangping Ding, and pn p. (2004) Involvement of the C-terminal propne-rich motif of G protein-coupled receptor kinases in recognition of activated rhodopsin. J. Biol. Chem. 279: 49741-49746.

8. Xiaoqing Gan, Jiyong Wang, Qiheng Yang, Zhong p, Feng pu, Gang Pei, and pn p. (2000) Interaction between the conserved region in the C-terminal domain of GRK2 and Rhodopsin is necessary for GRK2 to catalyze receptor phosphorylation. J. Biol. Chem. 275: 8469-8474.

 

Copyright 2012 ◎ 复旦大学基础医学院
地址:上海市医学院路138号 电话:21-54237900 传真: 021-64179832