Professors

Lei Liu

 

     LIU, Lei (1966-),Professor, Ph.D. of Cell biology from University of Connecticut. Dr. Liu currently serves as a PI of Institute of Biomedical Sciences of Fudan University and Deputy Director of Shanghai Center for Bioinformation Technology. Prior to that, he was the Director of Bioinformatics lab at University of Illinois at Urbana-Champaign. Liu’s research focuses on biomedical informatics, analysis of omics data, construction and analysis of biological network, system modeling, integration and mining of medical data, clinical decision support and personalized medicine. His featured accomplishments are as follows: He has been funded by  six projects of “863”Natioinal High Technology Projects and National Science and Technology Major Projects in the total amount of more than 20 million RMB,and published more than 60 articles in international peer-reviewed journals such as  Nucleic Acid Research, PLoS Computational Biology, Bioinformatics, etc., and develop a series of medical software systems, obtained over 20 software copyrights and 6 patents. 

 

Publications:

1. Hui Wang, Weide Zhang, Qiang Zeng, Zuofeng Li, ,Kaiyan Feng, Lei Liu*, Extracting important information from Chinese Operation Notes with natural language processing methods, Journal of Biomedical Informatics(Received 4 January 2013; accepted 13 December 2013. published online 19 February 2014). 
2. Juanjuan Xiao, Ying Wang, Zuofeng Li; Xufeng Zhang, Kaiyan Feng, Lei Liu*, Assessing the Gender Differences of Adverse Effects in HIV Infection Treatment Based on FDA AERS Database, Current Bioinformatics, 2013.5(8):583-590(8).
3. Bi-Qing Li, Hui Yu, Zheng Wang, Guohui Ding, Lei Liu*, MicroRNA mediated network and DNA Methylation in Colorectal Cancer, Protein Peptide Letter, 2013,3(20):1-12
4. Rudong Li and Lei Liu*. Characterizing criticality of proteins by systems dynamics: Escherichia coli central carbon metabolism as a working example. BMC Systems Biology, 2012,S11.
5. Bi-Qing Li, Tao Huang, Lei Liu*, Yu-Dong Cai*, Kuo-Chen Chou. Identification of Colorectal Cancer Related Genes with mRMR and Shortest Path in Protein-Protein Interaction Network. PLoS One, 2012,7(4):e33393
6. Zuofeng Li, Xingnan Liu, Jingran Wen, Ye Xu, Xin Zhao, Xuan Li, Lei Liu,*, and Xiaoyan Zhang* DRUMS: A Human Disease Related Unique Gene Mutation Search Engine. HUMAN MUTATION, 2011, 32:E2259-E2265 
7. Rudong Li, Yuanyuan Li, Ling-Yi Lu, Cong Ren, Yi-Xue Li, Lei Liu*. An improved kinetic model for the acetone-butanol-ethanol pathway of Clostridium acetobutylicum and model-based perturbation analysis. BMC Systems Biology, 2011, 5(Suppl.): S12.
8. Lele Hu, Lulu Zheng, Zhiwen Wang, Bing Li, Lei Liu*. Using Pseudo Amino Acid Composition to Predict Protease Families by Incorporating a Series of Protein Biological Features. Protein & Peptide Letters, 2011, 18(6):552-558.
9. Peng Jia, Liming Xuan, Lei Liu*, Chaochun Wei*. MetaBinG: Using GPUs to accelerate metagenomic sequence classification. PLoS One, 2011, 6(11):e25353. 
10. The role of Hepatitis C Virus in the dynamic protein interaction networks of hepatocellular cirrhosis and carcinoma, Tao Huang, Lei Liu, Qi Liu, Guohui Ding, Yejun Tan, Zhidong Tu, Yixue Li, *Hongyue Dai, *Lu Xie, International Journal of Computational Biology and Drug Design, Inderscience, 4(1), pp 5-17,  2011.

Department of Systems Biology for Medicine,School of Basic Medical Sciences of Fudan University copyright © 2014

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